FISH
Fluorescence in situ hybridization (FISH) and Sanger Sequencing solutions for advanced cytogenetic and molecular diagnostics.
Download Full Catalogue (PDF)What FISH Is Used For?
In oncological patients, FISH method is used to detect or confirm aberrations that cannot be identified by standard karyotyping. The FISH method is generally quite sensitive and it is also commonly used to monitor the treatment of patients with onco-hematological diseases. In non-oncological patients such prenatal diagnostics, FISH analysis complements and in certain cases replaces cytogenetic analysis of peripheral blood, amniotic fluid, and chorionic villus samples. FISH is used to confirm the cytogenetic findings and also to detect various aberrations that cannot be detected by karyotyping due to its low sensitivity, e.g., microdeletion syndromes.
FISH Advantages
FISH provides rapid, highly specific detection of chromosomal abnormalities. It does not require cell culturing for interphase FISH, allowing for faster turnaround times compared to standard karyotyping. It's an essential tool in Life Care's Solid Tumor and Blood Tumor diagnostics.
FISH Probe Characteristics
Our FISH probes are designed with high specificity and brightness, ensuring clear signals and low background noise. They are validated for use with various sample types including blood, bone marrow, and solid tumor tissues.